Compile Data Set for Download or QSAR
Found 549 from Nagoya City University
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586369(CHEMBL5094265)copy SMILES
Affinity DataKi:  5.30nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586368(CHEMBL5073848)copy SMILES
Affinity DataKi:  7.80nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240130(CHEMBL4060961)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240124(CHEMBL4090728)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using pLys4Met H3 peptide as substrate by peroxidase coupled UV-visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586370(CHEMBL5084197)copy SMILES
Affinity DataKi:  60nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240122(CHEMBL4103690)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586371(CHEMBL5089876)copy SMILES
Affinity DataKi:  80nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240126(CHEMBL4105288)copy SMILEScopy InChI
Affinity DataKi:  98nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586367(CHEMBL5089144)copy SMILES
Affinity DataKi:  100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586366(CHEMBL5093950)copy SMILES
Affinity DataKi:  100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50158884(CHEMBL3785550)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Inhibition of recombinant human His-tagged LSD1 (171 to 836 residues)/GST-tagged CoREST (308 to 440 residues) complex using H3K4 peptide substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586373(CHEMBL5075544)copy SMILES
Affinity DataKi:  170nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586365(CHEMBL5078239)copy SMILES
Affinity DataKi:  180nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240123(CHEMBL4085763)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240121(CHEMBL4089148)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586372(CHEMBL5085737)copy SMILES
Affinity DataKi:  640nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586364(CHEMBL5084292)copy SMILES
Affinity DataKi:  950nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50586363(CHEMBL5079374)copy SMILES
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6WFPPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240129(CHEMBL4080345)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210048(CHEMBL3884919)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50158884(CHEMBL3785550)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240131(CHEMBL4083113)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240118(CHEMBL4096854)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210048(CHEMBL3884919)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210048(CHEMBL3884919)copy SMILEScopy InChI
Affinity DataKi:  4.40E+4nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240125(CHEMBL4081282)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210049(CHEMBL3885101)copy SMILEScopy InChI
Affinity DataKi:  1.90E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210050(CHEMBL3884529)copy SMILEScopy InChI
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50210050(CHEMBL3884529)copy SMILEScopy InChI
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92D9VPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240116(CHEMBL4081041)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240117(CHEMBL4069633)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240120(CHEMBL4099300)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50240119(CHEMBL4104579)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QG1PubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490579(CHEMBL2337154)copy SMILEScopy InChI
Affinity DataIC50: 0.402nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490580(CHEMBL2337153)copy SMILEScopy InChI
Affinity DataIC50: 0.555nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490579(CHEMBL2337154)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490580(CHEMBL2337153)copy SMILEScopy InChI
Affinity DataIC50: 0.880nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490588(CHEMBL2336728)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490580(CHEMBL2337153)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of gamma-secretase in human HEK293 cells expressing APPNL/NotchDeltaE/EGFP/UAS-firefly luciferase assessed as inhibition of notch intracel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50502269(CHEMBL4446458)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of 5-(3-((1r,4r)-4-((5S,8S,11S,14S,17S,20S,29S)-11-((1H-imidazol-4-yl)methyl)-1,33-diamino-5-carbamoyl-17-(4-(4-(4-((4-(dimethylamino)phen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85TNPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490588(CHEMBL2336728)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490578(CHEMBL2337566)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490578(CHEMBL2337566)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50502269(CHEMBL4446458)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6P91PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50502268(CHEMBL4447813)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6P91PubMed
TargetPresenilin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50490578(CHEMBL2337566)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of gamma-secretase in human HEK293 cells expressing APPNL/NotchDeltaE/EGFP/UAS-firefly luciferase assessed as inhibition of notch intracel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251N3JPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50502278(CHEMBL4438193)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6P91PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
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