Affinity DataKi: 5.30nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using pLys4Met H3 peptide as substrate by peroxidase coupled UV-visible spectrophot...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of recombinant human His-tagged LSD1 (171 to 836 residues)/GST-tagged CoREST (308 to 440 residues) complex using H3K4 peptide substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human LSD1 using K4me2 peptide as substrate measured after 10 mins by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+4nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+4nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of human LSD1 assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human LSD1 (172 to 833 residues) assessed as reduction in H2O2 production using H3K4me2 (1 to 20 residues) peptide as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.402nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 0.555nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of gamma-secretase in human HEK293 cells expressing APPNL/NotchDeltaE/EGFP/UAS-firefly luciferase assessed as inhibition of notch intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of 5-(3-((1r,4r)-4-((5S,8S,11S,14S,17S,20S,29S)-11-((1H-imidazol-4-yl)methyl)-1,33-diamino-5-carbamoyl-17-(4-(4-(4-((4-(dimethylamino)phen...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta40 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in N2a NL/N cells coexpressing betaAPPNL and NotchdeltaE assessed as Abeta42 secretion by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of gamma-secretase in human HEK293 cells expressing APPNL/NotchDeltaE/EGFP/UAS-firefly luciferase assessed as inhibition of notch intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human SIRT2 defatty-acylase activity using SFP3 as substrate measured at 5 mins interval for 60 mins in presence of NAD+ by...More data for this Ligand-Target Pair